Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription (TaRGET)

Description

The TaRGET (Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription) Program is a research consortium funded by the National Institute of Environmental Health Sciences (NIEHS). The goal of the collaboration is to address the role of environmental exposures in disease pathogenesis as a function of epigenome perturbation, including understanding the environmental control of epigenetic mechanisms and assessing the utility of surrogate tissue analysis in mouse models of disease-relevant environmental exposures.

Update Frequency

TaRGET-DCC offers monthly data releases, although this dataset may not be updated at every release.

License

External data users may freely download, analyze, and publish results based on any TaRGET II data provided here without restrictions.

Documentation

https://data.targetepigenomics.org/

Managed By

TaRGET II Data Coordination Center (TaRGET-DCC)

See all datasets managed by TaRGET II Data Coordination Center (TaRGET-DCC).

Contact

targetdcc16@gmail.com

How to Cite

Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription (TaRGET) was accessed on DATE from https://registry.opendata.aws/targetepigenomics.

Usage Examples

Tutorials

• Finding and Downloading TaRGET II Data files by TaRGET-DCC
  

Tools & Applications

• Visualize TaRGET II data with WashU Epigenome Browser by WashU Epigenome Browser
  

Publications

• Comparison of differential accessibility analysis strategies for ATAC-seq data by Gontarz P, Fu S, Xing X, Liu S, Miao B et.al.
  
• Environmental Determinants of cardiovasular disease: lessons learned from air pollution by Al-Kindi SG, Brook RD, Biswal S, Rajagopalan S.
  
• Epigenetic biomarkers and preterm birth by Park B, Khanam R, Vinayachandran V, et.al.
  
• Metabolic effects of air pollution exposure and reversibility by Rajagopalan S, Park B, Palanivel R, et al.
  
• The NIEHS TaRGET II Consortium and environmental epigenomics by Wang, T., Pehrsson, E., Purushotham, D. et al.
  
• The role of environmental exposures and the epigenome in health and disease. by Perera BPU, Faulk C, Svoboda LK, Goodrich JM, Dolinoy DC.