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biotech blueprintchemistrygeneticgenomiclife sciencesmoleculeparquet
This a parquet representation of The Binding Database's Full BindingDB Database Dump that you can query straight from Athena in under 60 seconds (no Oracle database required). The Binding Database projects aims to make experimental data on the noncovalent association of molecules in solution searchable via the world wide web. The initial focus is on biomolecular systems, but data on host-guest and supramolecular systems are also important and being included over time. It is expected that the enhanced access to data provided by this resource will facilitate drug-discovery, the design of sel...
biotech blueprintchemistrygenomiclife sciencesmoleculeparquet
ChEMBL is a manually curated database of bioactive molecules with drug-like properties. It brings together chemical, bioactivity and genomic data to aid the translation of genomic information into effective new drugs. This representation of ChEMBL is stored in Parquet format and most easily utilized through Amazon Athena. Follow the documentation for install instructions (< 2 minute install). New ChEMBL releases occur sporadically; the most up to date information on ChEMBL releases can be found here.
biotech blueprintchemistrygeneticgenomiclife sciencesparquet
ClinVar is a freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence. ClinVar thus facilitates access to and communication about the relationships asserted between human variation and observed health status, and the history of that interpretation. ClinVar processes submissions reporting variants found in patient samples, assertions made regarding their clinical significance, information about the submitter, and other supporting data. The alleles described in submissions are mapped to reference sequences, and reported acc...
biotech blueprintchemistrygeneticgenomiclife sciencesmoleculeparquet
This a Parquet representation of the Open Targets Platform's latest export. The Open Targets Platform integrates evidence from genetics, genomics, transcriptomics, drugs, animal models and scientific literature to score and rank target-disease associations for drug target identification. The Open Targets Platform (https://www.targetvalidation.org) is a freely available resource for the integration of genetics, genomics, and chemical data to aid systematic drug target identification and prioritisation. This dataset is 'Lakehouse Ready'. Meaning, you can query this data in-place straight out of the Registry of Open Data S3 bucket. Deploy this dataset's corresponding CloudFormation template to create the AWS Glue catalog entries into your account in about 30 seconds. That one step will enable you to write SQL with AWS Athena, build dashboards and charts with Amazon Quick...
bioinformaticsbiologybiotech blueprintgeneticgenomiclife sciencesparquetpopulation geneticsvcfwhole genome sequencing
The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators that aggregates and harmonizes both exome and genome data from a wide range of large-scale human sequencing projects Sign up for the gnomAD mailing list here. This dataset was derived from summary data from gnomAD release 3.1, ava...