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SnpEff & SnpSift Genomic Variant Annotation Databases

bioinformatics cancer genetic genome genomic life sciences protein structural variation transcriptomics variant annotation vcf whole exome sequencing whole genome sequencing

Description

SnpEff is a variant annotation and effect prediction tool that annotates and predicts the effects of genetic variants on genes and proteins (such as amino acid changes). It supports over 38,000 genomes and provides comprehensive genomic databases for variant annotation. The databases include reference genomes, gene annotations, protein sequences, and regulatory elements from trusted sources like ENSEMBL, RefSeq, and UCSC. SnpSift complements SnpEff by providing tools to annotate genomic variants using databases, filter large genomic datasets, and manipulate annotated variants. Together, these tools provide a complete solution for genomic variant analysis, supporting research in human genetics, cancer genomics, pharmacogenomics, and model organism studies.

Update Frequency

Monthly

License

MIT License

Documentation

https://pcingola.github.io/SnpEff/

Managed By

Pablo Cingolani

See all datasets managed by Pablo Cingolani.

Contact

Pablo Cingolani http://www.linkedin.com/in/pablocingolani

How to Cite

SnpEff & SnpSift Genomic Variant Annotation Databases was accessed on DATE from https://registry.opendata.aws/snpeff.

Usage Examples

Tutorials
Tools & Applications
Publications

Resources on AWS

  • Description
    SnpEff databases for genomic variant annotation
    Resource type
    S3 Bucket
    Amazon Resource Name (ARN)
    arn:aws:s3:::snpeff-public
    AWS Region
    us-east-2
    AWS CLI Access (No AWS account required)
    aws s3 ls --no-sign-request s3://snpeff-public/

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