Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) Raw Data

Description

The Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) study provides transcriptomic and chromatin accessibility data from single nuclei isolated from postmortem brain tissue from individuals spanning the Alzheimer's disease spectrum. The study supports investigation of cellular and molecular changes associated with Alzheimer's disease progression and includes data generated as part of the broader SEA-AD effort to characterize brain cell types, disease-associated cellular states, and related neuropathology.

Update Frequency

AD Knowledge Portal Data Releases are published monthly (https://news.adknowledgeportal.org/). Updates to specific studies are dependent on data contributor and ingress timelines.

License

https://adknowledgeportal.synapse.org/Explore/Studies/DetailsPage/StudyDetails?Study=syn26223298#Acknowledgement

Documentation

https://doi.org/10.7303/9618137

Managed By

Sage Bionetworks

See all datasets managed by Sage Bionetworks.

Contact

https://www.synapse.org/Synapse:syn2580853/discussion/default

How to Cite

Seattle Alzheimer's Disease Brain Cell Atlas (SEA-AD) Raw Data was accessed on DATE from https://registry.opendata.aws/sage-sea-ad-atlas. The results published here are in whole or in part based on data obtained from the AD Knowledge Portal (NIH-NIA, U24AG061340).

Usage Examples

Publications

• SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease by Hawrylycz M, Kaplan ES, Travaglini KJ, Gabitto MI, Miller JA, Ng L, et al.