The Religious Orders Study and Memory and Aging Project (ROSMAP) Study

Description

The Religious Orders Study (ROS) and Rush Memory and Aging Project (MAP) are ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease. Participants enroll without known dementia, undergo annual clinical and cognitive evaluations, and agree to organ donation at death. The ROSMAP study provides genomic, transcriptomic, epigenomic, proteomic, metabolomic, imaging, and related metadata generated from these cohorts to support research into cognitive decline, neuropathology, brain aging, and the molecular mechanisms of Alzheimer's disease.

Update Frequency

AD Knowledge Portal Data Releases are published monthly (https://news.adknowledgeportal.org/). Updates to specific studies are dependent on data contributor and ingress timelines.

License

https://adknowledgeportal.synapse.org/Explore/Studies/DetailsPage/StudyDetails?Study=syn3219045#Acknowledgement

Documentation

https://doi.org/10.7303/9618239

Managed By

Sage Bionetworks

See all datasets managed by Sage Bionetworks.

Contact

https://www.synapse.org/Synapse:syn2580853/discussion/default

How to Cite

The Religious Orders Study and Memory and Aging Project (ROSMAP) Study was accessed on DATE from https://registry.opendata.aws/rosmap.

Usage Examples

Publications

• A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease by Oh HS, Urey DY, Karlsson L, Zhu Z, Shen Y, Farinas A, et al.
  
• A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research by De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, et al.
  
• Religious Orders Study and Rush Memory and Aging Project by Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA