NIH Roadmap Epigenomics

Description

The NIH Roadmap Epigenomics Mapping Consortium was launched with the goal of producing a public resource of human epigenomic data to catalyze basic biology and disease-oriented research. The project has generated high-quality, genome-wide maps of several key histone modifications, chromatin accessibility, DNA methylation and mRNA expression across 100s of human cell types and tissues.

Update Frequency

NIH Roadmap Epigenomics Mapping Consortium ended, no updates would be provided.

License

External data users may freely download, analyze, and publish results based on any NIH Roadmp Epigenomics data provided here without restrictions.

Documentation

https://egg2.wustl.edu/roadmap/web_portal/

Managed By

NIH Roadmap Epigenomics Mapping Consortium, Ting Wang Lab at WashU (https://wang.wustl.edu/)

See all datasets managed by NIH Roadmap Epigenomics Mapping Consortium, Ting Wang Lab at WashU (https://wang.wustl.edu/).

Contact

dli23@wustl.edu

How to Cite

NIH Roadmap Epigenomics was accessed on DATE from https://registry.opendata.aws/roadmapepigenomics.

Usage Examples

Tutorials

• Navigation of Roadmap data using Roadmap web portal by Anshul Kundaje Lab
  
• Visualize TaRGET data with WashU Epigenome Browser by WashU Epigenome Browser
  

Publications

• Chromatin architecture reorganization during stem cell differentiation by GJesse R. Dixon, Inkyung Jung, Siddarth Selvaraj, Yin Shen, Jessica E. Antosiewicz-Bourget, Ah Young Lee, Zhen Ye, Audrey Kim, Nisha Rajagopal, Wei Xie, Yarui Diao, Jing Liang, Huimin Zhao, Victor V. Lobanenkov, Joseph R. Ecker, James A. Thomson & Bing Ren
  
• Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease. by Elizabeta Gjoneska, Andreas R. Pfenning, Hansruedi Mathys, Gerald Quon, Anshul Kundaje, Li-Huei Tsai & Manolis Kellis.
  
• Human body epigenome maps reveal noncanonical DNA methylation variation by Matthew D. Schultz, Yupeng He, John W. Whitaker, Manoj Hariharan, Eran A. Mukamel, Danny Leung, Nisha Rajagopal, Joseph R. Nery, Mark A. Urich, Huaming Chen, Shin Lin, Yiing Lin, Inkyung Jung, Anthony D. Schmitt, Siddarth Selvaraj, Bing Ren, Terrence J. Sejnowski, Wei Wang & Joseph R. Ecker
  
• Integrative analysis of 111 reference human epigenomes by Roadmap Epigenomics Consortium, Anshul Kundaje, Wouter Meuleman, Jason Ernst, Misha Bilenky, Angela Yen, Alireza Heravi-Moussavi, Pouya Kheradpour etc.al, Ting Wang, Manolis Kellis
  
• The epigenomic landscape of transposable elements across normal human development and anatomy by Erica C. Pehrsson, Mayank N. K. Choudhary, Vasavi Sundaram & Ting Wang
  
• WashU Epigenome Browser update 2019 by Daofeng Li, Silas Hsu, Deepak Purushotham, Renee L Sears and Ting Wang