This study generated a collection of patient-derived pancreatic normal and cancer organoids and it was sequenced using Whole Genome Sequencing (WGS), Whole Exome Sequencing (WXS) and RNA-Seq as well as matched tumor and normal tissue if available. The study provides a valuable resource for pancreatic cancer researchers. The dataset contains open RNA-Seq Gene Expression Quantification data and controlled WGS/WXS/RNA-Seq Aligned Reads, WXS Annotated Somatic Mutation, WXS Raw Somatic Mutation, and RNA-Seq Splice Junction Quantification.
Genomic Data Commons (GDC) is source of truth for this dataset; GDC offers monthly data releases, although this dataset may not be updated at every release.
NIH Genomic Data Sharing Policy: https://gdc.cancer.gov/access-data/data-access-policies
See all datasets managed by Center for Translational Data Science at The University of Chicago.
Pancreatic Cancer Organoid Profiling was accessed on
DATE from https://registry.opendata.aws/organoid-pancreatic.
aws s3 ls --no-sign-request s3://gdc-organoid-pancreatic-phs001611-2-open/