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Genomic Characterization of Metastatic Castration Resistant Prostate Cancer

cancer genomic life sciences STRIDES whole genome sequencing


Biopsies of castration resistant prostate cancer metastases were subjected to whole genome sequencing (WGS), along with RNA-sequencing (RNA-Seq). The overarching goal of the study is to illuminate molecular mechanisms of acquired resistance to therapeutic agents, and particularly androgen signaling inhibitors, in the treatment of metastatic castration resistant prostate cancer (mCRPC). This study is made available on AWS via the NIH STRIDES Initiative.

Update Frequency

Genomic Data Commons (GDC) is source of truth for this dataset; GDC offers monthly data releases, although this dataset may not be updated at every release.


NIH Genomic Data Sharing Policy:


Managed By

See all datasets managed by Center for Translational Data Science at The University of Chicago.


How to Cite

Genomic Characterization of Metastatic Castration Resistant Prostate Cancer was accessed on DATE from dbGaP accession phs001648.v2.p1

Usage Examples

Tools & Applications

Resources on AWS

  • Description
    Whole Genome Sequencing, RNA Sequencing
    Resource type
    S3 Bucket
    Amazon Resource Name (ARN)
    AWS Region
    AWS CLI Access (No AWS account required)
    aws s3 ls --no-sign-request s3://gdc-wcdt-mcrpc-phs001648-2-open/

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