Gabriella Miller Kids First Pediatric Research Program (Kids First)

cancer genetic genomic Homo sapiens life sciences pediatric structural birth defect whole genome sequencing

Description

The NIH Common Fund's Gabriella Miller Kids First Pediatric Research Program’s (“Kids First”) vision is to “alleviate suffering from childhood cancer and structural birth defects by fostering collaborative research to uncover the etiology of these diseases and by supporting data sharing within the pediatric research community.” The program continues to generate and share whole genome sequence data from thousands of children affected by these conditions, ranging from rare pediatric cancers, such as osteosarcoma, to more prevalent diagnoses, such as congenital heart defects. In 2018, Kids First launched the Gabriella Miller Kids First Data Resource Center, charged with building a large-scale data platform supporting clinical and genetic data from these patients and their families in order to accelerate discovery and ultimately clinical impact. Researchers can search, access, aggregate, and analyze these data through the Kids First Data Resource Portal. Additionally, by using cloud-based individual workspaces in CAVATICA, a data analysis and sharing computation platform, researchers can cross-analyze Kids First data with data from other efforts, such as NCI’s TARGET program and consortia-based datasets like the Children’s Brain Tumor Tissue Consortium (CBTTC).

Update Frequency

Data is updated on a rolling basis by the KFDRC to make data available as rapidly as possible under the NIH Genomic Data Sharing Policy.

License

NIH Genomic Data Sharing Policy: https://gdc.cancer.gov/access-data/data-access-policies

Documentation

https://kidsfirstdrc.org/

Managed By

The Gabriella Miller Kids First Data Resource Center (KFDRC) at the Children's Hospital of Philadelphia

See all datasets managed by The Gabriella Miller Kids First Data Resource Center (KFDRC) at the Children's Hospital of Philadelphia.

Contact

support@kidsfirstdrc.org

Usage Examples

Tools & Applications
Publications

Resources on AWS

  • Description
    Kids First: Pediatric Research Project on the Genomic Analysis of Congenital Diaphragmatic Hernia
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-46sk55a3
    AWS Region
    us-east-1
  • Description
    National Heart, Lung, and Blood Institute (NHLBI) Bench to Bassinet Program: The Gabriella Miller Kids First Pediatric Research Program of the Pediatric Cardiac Genetics Consortium (PCGC)
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-preasa7s
    AWS Region
    us-east-1
  • Description
    Gabriella Miller Kids First (GMKF) Pediatric Research Program in Susceptibility to Ewing Sarcoma Based on Germline Risk and Familial History of Cancer
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-ygva0e1c
    AWS Region
    us-east-1
  • Description
    Kids First: Genomic Studies of Orofacial Cleft Birth Defects
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-9pyzahhe
    AWS Region
    us-east-1
  • Description
    GMKF: Kids First Pediatric Research Program on Congenital Cranial Dysinnervation Disorders and Related Birth Defects
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-dztb5hrr
    AWS Region
    us-east-1
  • Description
    Kids First: Pediatric Research Project on Adolescent Idiopathic Scoliosis
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-rm8afw0r
    AWS Region
    us-east-1
  • Description
    Disorders/Differences of Sex Development (DSD) Study Performed at UCLA in Collaboration with the DSD-Translational Research Network (DSD-TRN), with the Support of the Gabriella Miller Kids First Pediatric Research Program
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-6fpyjqbr
    AWS Region
    us-east-1
  • Description
    Kids First: Genomics of Orofacial Cleft Birth Defects in Latin American Families
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-r0eprsgs
    AWS Region
    us-east-1
  • Description
    Kids First: Genomics of Orofacial Cleft Birth Defects in Latin American Families
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-r0eprsgs
    AWS Region
    us-east-1
  • Description
    Discovering the Genetic Basis of Human Neuroblastoma: A Gabriella Miller Kids First Pediatric Research Program (Kids First) Project
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-dypmehhf
    AWS Region
    us-east-1
  • Description
    Gabriella Miller Kids First Pediatric Research Program in Enchondromatoses and Related Malignant Tumors
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-7nq9151j
    AWS Region
    us-east-1
  • Description
    Kids First Pediatric Research Study in Familial Predisposition to Hematopoietic Malignancies (SJFAMILY-HM)
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-vttshwv4
    AWS Region
    us-east-1
  • Description
    Gabriella Miller Kids First Pediatric Research Program in Whole Genome Sequencing of African and Asian Orofacial Clefts Case-Parent Triads
    Resource type
    S3 Bucket Controlled Access
    Amazon Resource Name (ARN)
    arn:aws:s3:::kf-study-us-east-1-prd-sd-dk0krwk8
    AWS Region
    us-east-1

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