Safety and Preliminary Efficacy of Intranasal Insulin for Cognitive Impairment in Parkinson Disease and Multiple System Atrophy

Description

This dataset was collected as part of a study that aimed to determine the effects of intranasal insulin (INI) on cognition and motor performance in PD. The study was a proof of concept, randomized, double-blinded, placebo-controlled trial evaluating the effects of 40 international units (IU) of insulin or saline once daily for four weeks on cognitive and functional performance. Of 16 subjects enrolled, eight in the INI group and six in the placebo group completed verbal fluency (FAS), Unified Parkinson Disease Scale (UPDRS), and modified Hoehn and Yahr scale (HY, PD severity) at baseline and post-treatment and were included in the analyses.

Update Frequency

Not updated

License

Open Data Commons Attribution License v1.0

Documentation

https://doi.org/10.13026/bn1x-my19

Managed By

PhysioNet

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Contact

https://physionet.org/about/#contact_us

How to Cite

Safety and Preliminary Efficacy of Intranasal Insulin for Cognitive Impairment in Parkinson Disease and Multiple System Atrophy was accessed on DATE from https://registry.opendata.aws/inipdmsa.