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The Impact of Variation on Function Consortium (IGVF)

bioinformatics biology genetic genomic life sciences

Description

The IGVF (Impact of Genomic Variation on Function) Consortium aims to understand how genomic variation affects genome function, which in turn impacts phenotype. The NHGRI is funding this collaborative program that brings together teams of investigators who will use state-of-the-art experimental and computational approaches to model, predict, characterize and map genome function, how genome function shapes phenotype, and how these processes are affected by genomic variation. These joint efforts will produce a catalog of the impact of genomic variants on genome function and phenotypes.
The Data Corpus consists of single-cell Genomics experiments (both single modal, and multimodal, typically snRNA-seq and snATAC-seq), Characterization experiments using Massively Parallel Reporter Assays (MPRAs) and CRISPR-screens along with a variety of protein mutatation assays, and Predictive Models. There are a huge variety of files in IGVF that are stored in the AWS OpenData Set so we recommend using the metadata file or browsing the IGVF Data Portal

Update Frequency

Daily

License

CC BY 4.0 - https://creativecommons.org/licenses/by/4.0/ - You are free to share and adapt this data with proper attribution

Documentation

https://data.igvf.org/general-help

Managed By

IGVF Data Administration and Coordination Center at Stanford University

See all datasets managed by IGVF Data Administration and Coordination Center at Stanford University.

Contact

igvf-portal-help@lists.stanford.edu

How to Cite

The Impact of Variation on Function Consortium (IGVF) was accessed on DATE from https://registry.opendata.aws/igvf-consortium.

Usage Examples

Tutorials
Tools & Applications
Publications

Resources on AWS

  • Description
    Released and Archived IGVF Data Files
    Resource type
    S3 Bucket
    Amazon Resource Name (ARN)
    arn:aws:s3:::igvf-public
    AWS Region
    us-west-2
    AWS CLI Access (No AWS account required)
    aws s3 ls --no-sign-request s3://igvf-public/
  • Description
    Notifications for new IGVF data
    Resource type
    SNS Topic
    Amazon Resource Name (ARN)
    arn:aws:sns:us-west-2:407227577691:igvf-public-object_created
    AWS Region
    us-west-2

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