Encyclopedia of DNA Elements (ENCODE)

biology bioinformatics genetic genomic life sciences machine learning deep learning

Description

The Encyclopedia of DNA Elements (ENCODE) Consortium is an international collaboration of research groups funded by the National Human Genome Research Institute (NHGRI). The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active. ENCODE investigators employ a variety of assays and methods to identify functional elements. The discovery and annotation of gene elements is accomplished primarily by sequencing a diverse range of RNA sources, comparative genomics, integrative bioinformatic methods, and human curation. Regulatory elements are typically investigated through DNA hypersensitivity assays, assays of DNA methylation, and immunoprecipitation (IP) of proteins that interact with DNA and RNA, i.e., modified histones, transcription factors, chromatin regulators, and RNA-binding proteins, followed by sequencing.

Update Frequency

Daily

License

External data users may freely download, analyze, and publish results based on any ENCODE data without restrictions.

Documentation

https://www.encodeproject.org

Managed By

ENCODE Data Coordinating Center

See all datasets managed by ENCODE Data Coordinating Center.

Contact

encode-help@lists.stanford.edu

Usage Examples

Resources on AWS

  • Description
    Released and archived ENCODE data
    Resource type
    S3 Bucket
    Amazon Resource Name (ARN)
    arn:aws:s3:::encode-public
    AWS Region
    us-west-2

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