Knowledge Portal Network Bottom-line Genetic Associations

Description

At the Knowledge Portal Network, we aggregate and analyze genetic association results for a wide range of diseases and traits. For any given disease, a large number of individual genetic association datasets may have been generated. To make these results more interpretable, we meta-analyze all datasets for each phenotype, using a method that we term "bottom-line integrative analysis". Here we provide the bottom-line summary statistic files for public download.

Update Frequency

Three times per year

License

https://a2f.hugeamp.org/policies.html

Documentation

https://kp4cd.org/bottom-line_associations

Managed By

Jason Flannick lab, Broad Institute of MIT and Harvard

See all datasets managed by Jason Flannick lab, Broad Institute of MIT and Harvard.

Contact

help@kp4cd.org

How to Cite

Knowledge Portal Network Bottom-line Genetic Associations was accessed on DATE from https://registry.opendata.aws/dig-open-analysis-data. Knowledge Portal Network Bottom-line Genetic Associations for [PHENOTYPE] were accessed on [DATE] at registry.opendata.aws/[dataset]

Usage Examples

Tutorials

• Tutorial: Use cases for the Knowledge Portal Network bottom-line genetic associations by Jason Flannick
  

Publications

• Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research by Costanzo MC, Roselli C, Brandes M, Duby M, Hoang Q, Jang D, et al.
  
• Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal by Kudtarkar P, Costanzo MC, Sun Y, Jang D, Koesterer R, Mychaleckyj JC, et al.
  
• The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits by Costanzo MC, von Grotthuss M, Massung J, Jang D, Caulkins L, Koesterer R, et al.