health life sciences medicine
Acute Brain injury (ABI) is a devastating event requiring intensive acute treatment and post-injury rehabilitation, both delivered for indeterminate periods of time. For severe ABIs, acute treatment is aimed at stabilizing the patient to prevent secondary brain injury from ischemia and swelling. This requires a balance between adequate levels of cerebral blood flow and safely low intracranial pressure (ICP) - a task normally done by autoregulatory (AR) processes of the brain. In the absence of normal AR, hemodynamic stability is difficult to maintain because there are no reliable predictors to guide treatment. Thus, guidelines for triage and discharge are somewhat arbitrary for ABI and the need for a Clinical Decision Support (CDS) system for neurotrauma is widely recognized. Prerequisite to a CDS is a large database of patient records and efficient means to extract meaningful information from them. CHARIS will systematize the analysis of relevant physiological signals, and will embody data-driven algorithms to search for potential predictors of acute clinical events.
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Cerebral Haemodynamic Autoregulatory Information System GUI was accessed on DATE from https://registry.opendata.aws/charis-gui.
arn:aws:s3:::physionet-open/charis-gui/us-east-1aws s3 ls --no-sign-request s3://physionet-open/charis-gui/